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Dr. Nathan Bryan: Why Nitric Oxide Is Important

Dr. Nathan Bryan and Susan Shaffer are the founders of Pneuma Nitric Oxide LLC., and recently generously donated their time to speak about the benefits of Nitric Oxide and why it’s important for maintaining overall health on a recent Facebook Live

What is Nitric Oxide?

“Our cardiovascular system relies on Nitric Oxide. So, no matter your age or stage of life, N-O is critical to your health. This is especially poignant when you consider that millions of Americans have blood pressure in the higher range of normal.

This essential molecule signals our blood vessels to relax and expand, creating greater efficiency in the body, greater nutrient delivery, greater oxygenation and so on to every system, organ and tissue in the body. It also supports healthy blood pressure. The point is that N-O is truly linked to everything we do and every breath we take.” –

Adequate Nitric Oxide production is required for optimal health & cellular function.


It is incredibly important to be aware of what your nitric oxide production capacity is, and then employ strategies to restore the production of nitric oxide in your body. 

Dr. Nathan Bryan has been studying nitric oxide for over 20 years to answer four fundamental questions. How does the body make nitric oxide? What goes wrong in people that can’t make it? What are the clinical consequences of that, and then how do you fix these underlying problems? And in those 20 years, there have been some phenomenal discoveries in creating technology that addresses the global nitric oxide problem.

Nitric oxide is a signaling molecule that tells the cells in our body to communicate. It relaxes blood vessels and increases oxygen and nutrient delivery to every cell in the body and provides essential electrons, which is an important component of energetic medicine. All electron donors provide voltage and affect the pH of the cell. It’s also how our immune system works, so in the time of coronavirus, Dr. Bryan and his colleagues are finding that people who are nitric oxide deficient are the ones that are more susceptible to disease, and those nitric oxide deficient patients are the ones that do poorly in terms of hospitalization and disease severity. So nitric oxide is not just important in maintaining the integrity of the cardiovascular system and nutrient/oxygen delivery, but really it’s how the body fights off infections. According to Dr. Bryan, the single most important thing you can do during this time is to restore your nitric oxide levels. That way, your circulation improves and your immune system is able to combat viruses and bacterial infections. 

“Nitric oxide (NO) [is a] simple molecule that controls oxygen and nutrient delivery to every cell in the body, it regulates cellular communication.  All of which affect the signs of aging.” – Pneuma Nitric Oxide™

What does the Pneuma Nitric Oxide™ Skin Serum do?

You can restore systemic production of nitric oxide in the body through the neo40 lozenge, and topically (for cosmetic & anti-aging effects) with Pneuma Nitric Oxide™ Skin Serum.

2 peer-reviewed published clinical trials were recently published on the Pneuma Nitric Oxide™ Skin Serum looking at the effects of fine lines and wrinkles from a cosmetic perspective, and also in acne, which found in 30 days, there is a vast improvement. Through dual-chamber technology, nitric oxide is generated and when it is applied to the skin, one can see the increase in blood flow and circulation as the area recruits small vessels and turns pink. Whether it’s a loss of hydration, fine lines/wrinkles or some type of acne or inflammation, all of that is a consequence of reduced blood flow, and so when you apply the serum to the face you open up the small blood vessels, infuse the cells of the dermis, and then they can do their job to heal.

Purchase Pneuma Nitric Oxide 

What is the N1O1 lozenge?

As we mentioned before, every single chronic disease is characterized by reduced blood flow and oxygen delivery to the affected organ, whether it’s heart disease, vascular dementia and Alzheimer’s, diabetes and peripheral neuropathy, or macular degeneration of the eyes. All of those result from insufficient blood flow to those areas of the body, and so one cannot correct any chronic disease until blood flow is regulated to that affected organ. If someone is taking supplements to give the body the missing nutrients that it needs, that person needs to restore the production of nitric oxide in order to deliver those nutrients to the individual cells. Neo40 is an orally disintegrating tablet developed over ten years ago that generates nitric oxide if your body can’t make it on its own. It’s the only technology in the world that creates nitric oxide gas by activating with the saliva. 


Ten Facts about Nitric Oxide (NO) (from this site)


1. Nitric oxide is one of the most important molecules produced in the human body.

2. NO is a potent vasodilator that keeps your arteries open and blood flowing to every cell in your body.

3. Nitric oxide is made by every cell in your body; however, production declines by 10-12% per decade starting in the early 20s.  By age 40-50, we make only 50%.

4. Loss of NO production is associated with the normal aging process.

5. Prescription drugs, such as proton pump inhibitors, NSAIDS, antibiotics, antiseptic mouthwash, and cholesterol-lowering statin drugs block the production of NO.

6. Most people do not know what nitric oxide is or why it is critical that they employ strategies to restore nitric oxide.

7. NO has been shown to dilate blood vessels and recruit new blood vessels, improving circulation to regions as it is produced or supplied.

8. NO has potent anti-inflammatory properties that help combat free radicals that damage cells and cause premature aging.

9. NO is responsible for cellular energy production and cell metabolism which keeps cells healthy and functional.

10. Due to diet, lifestyle, and many drug therapies, most Americans are deficient in nitric oxide. 

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